A heartfelt look back at the life, music, and legacy of Cleto Escobedo III, who helped define the spirit of late-night television for more than two decades.
When audiences tuned in to Jimmy Kimmel Live! each night, one sound always set the tone — the smooth, brassy rhythms of Cleto and the Cletones, led by the charismatic Cleto Escobedo III.
On November 11, 2025, fans and friends around the world were heartbroken to learn of Escobedo’s passing at the age of 59. More than a bandleader, he was the heartbeat of the show — and a lifelong friend to Jimmy Kimmel himself.
While the official cause of death has not been confirmed, tributes from across the entertainment world continue to pour in, celebrating his warmth, humor, and musical genius.
Cleto Escobedo III: Early Life and Musical Roots
Born and raised in Las Vegas, Nevada, Cleto Escobedo III grew up surrounded by music. His father, Cleto Escobedo II, was a respected saxophonist and performer, passing down a deep love of jazz and funk to his son.
Cleto’s childhood also included another soon-to-be famous figure — Jimmy Kimmel, who lived just across the street. The two developed a friendship that would last a lifetime, bound by humor, loyalty, and a shared dream of doing what they loved.
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Escobedo’s early musical career took him through local Vegas clubs and studio sessions, where he quickly became known for his soulful saxophone style and magnetic stage presence.
From Vegas to Hollywood: The Making of Cleto and the Cletones
When Jimmy Kimmel Live! premiered in 2003, Kimmel didn’t have to think twice about who should lead his house band. He called his childhood friend Cleto — and thus began a new era in late-night music.
Under Escobedo’s leadership, Cleto and the Cletones became an integral part of the show’s identity. Their jazzy intros, spontaneous riffs, and chemistry with Kimmel gave the program a unique blend of fun and authenticity.
Cleto’s personality shone through every performance — humble, humorous, and effortlessly cool. He wasn’t just a musician on camera; he was family to the entire Jimmy Kimmel Live! team.
A Bond Beyond Television: Cleto and Jimmy’s Lifelong Friendship
In his emotional on-air tribute, Jimmy Kimmel described Cleto as “my first best friend — inseparable since I was nine years old.”
Their relationship transcended show business; they were like brothers. Whether roasting each other on air or sharing tender backstage moments, their connection reflected genuine friendship and trust.
Fans often noted how Cleto’s presence grounded Kimmel — balancing comedy with heart. It’s rare in Hollywood to see that kind of lifelong loyalty, and their partnership became one of late-night TV’s most cherished stories.
Tributes and Legacy
Following his passing, musicians, celebrities, and fans flooded social media with tributes. Legendary drummer Sheila E., a close collaborator, wrote that she was “devastated” but grateful to have performed alongside “one of the kindest souls in music.”
Industry peers praised his professionalism and humility, calling him a rare blend of talent and grace. Beyond television, Cleto mentored young artists and inspired countless saxophonists to pursue jazz and live performance.
Though the cause of death has not been officially confirmed, reports suggest health complications following a liver transplant earlier this year. Jimmy Kimmel’s heartfelt words — “He was the best man I’ve ever known” — summed up what so many felt.
Cleto Escobedo III’s Lasting Impact
Cleto’s legacy isn’t measured only in performances but in the joy he brought to millions. For over 20 years, he turned late-night TV into a nightly concert — proving that great music and friendship can elevate entertainment to something timeless.
Even in his absence, Cleto and the Cletones will continue to remind audiences of his laughter, kindness, and groove that defined an era.
Conclusion
Cleto Escobedo III wasn’t just a bandleader; he was the soul of Jimmy Kimmel Live! — a friend, father, and artist whose music united people night after night.
His story reminds us that the best legacies are built not only on fame or talent, but on love, loyalty, and laughter shared with those who matter most.
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